The ‘mu’ variant, also known as B.1.621, was first identified in Taiwan and has since been reported in several other countries. This variant is characterized by a number of mutations that could potentially make it more resistant to current vaccines. Taiwan has seen a recent increase in COVID-19 cases, with a significant proportion attributed to the ‘mu’ variant. This rise in cases has prompted concerns about the country’s capacity to contain the virus and maintain its impressive track record in managing the pandemic. Despite the potential for vaccine resistance, the importance of vaccination remains paramount. Vaccines have proven to be effective in preventing serious illness and death, even in the face of new variants. Will the world overcome the Covid-19 pandemic ?