Tuberculosis is still one of the deadliest infectious diseases, causing over one million deaths each year worldwide.The current anti-tuberculosis vaccine, BCG, is administered worldwide. However, considering that more than 10 million new tuberculosis cases are reported each year, its effectiveness is deemed insufficient.In developing tuberculosis vaccines, scientists have studied proteins from M. tuberculosis that trigger protective immunity against tuberculosis. IFN-gamma produced by T cells is especially known to be critical for protection against tuberculosis. Can the world eliminate the killer disease through vaccines ?

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